Journal Reviews

Allergy journal cover image

Allergic rhinitis, the usual suspects

27 February 2020 | | Rhinology / Sinus | allergic rhinitis, cysteinyl leukotriene, eosinophil, group 2 innate lymphoid cells, prostaglandin D2

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...